产品货号：
Z37004
中文名称：
Hu CD64/FCGR1A Purified抗体
英文名称：
Anti-Hu CD64/FCGR1A Purified Antibody (Clone#10.1)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Hu CD64/FCGR1A Purified Antibody (Clone#10.1) |
| 指标别名 | CD64;CD64A;Fc gamma RI;Fc gamma RIA;FCG1;FcgammaRIa;FCGR1;FCGR1A;FCRI;IGFR1;IgG Fc receptor I |
| 克隆性 | Monoclonal |
| 检验物种 | human,primate |
| 应用范围 | FCM,IP,WB,IHC,IHC-F,ICC |
| 基因名称 | FCGR1A |
| 克隆号 | 10.1 |
| 抗体来源 | Mouse |
| 免疫原 | Rheumatoid synovial fluid cells and fibronectin purified human monocytes.The mouse monoclonal antibody 10.1 recognizes an extracellular epitope on CD64/FcgammaRI,a 72kDa single chain type I glycoprotein,that is expressed on monocytes/macrophages,dendritic cells,and activated granulocytes. |
| 计算分子量 | 43kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD64 (FcgammaRI) is a cell surface receptor for Fc region of IgG.It is composed of specific ligand binding alpha subunit and promiscuous gamma subunit,which is indispensable for tyrosine-based signaling.However,even the alpha subunit can transduce signals leading to cellular effector functions.The isoform FcgammaRIa1 binds human IgG with high affinity,has limited myeloid cell distribution,and a relatively large intracellular domain.Products of related genes include FcgammaRIb and FcgammaRIc isoforms,but these specify low affinity IgG receptors if functionally expressed at all.Besides a role in antigen clearance,FcgammaRI (a1) can potently enhance MHC class I and II antigen presentation in vitro and in vivo. |
| Uniprot ID | P12314 |
| 基因名全称 | Fc fragment of IgG receptor Ia |
| 蛋白名全称 | High affinity immunoglobulin gamma Fc receptor I |
| 推荐稀释比 | Flow cytometry:1～5μg/mL. |
相关搜索：Hu CD64/FCGR1A Purified抗体，Hu CD64抗体，FCGR1A Purified单抗